Glucose utilization by fetal muscles during maternal fasting.
نویسندگان
چکیده
In utero, glucose utilization by fetal muscles (heart and hindlimb) displays important interspecies differences. In the fed state, it is 5-fold higher in rat than in rabbit fetal muscles. Maternal fasting induces a decrease in glucose utilization in fetal muscles of the rat but not of the rabbit.
منابع مشابه
Adrenal glands are essential for activation of glucogenesis during undernutrition in fetal sheep near term.
In adults, the adrenal glands are essential for the metabolic response to stress, but little is known about their role in fetal metabolism. This study examined the effects of adrenalectomizing fetal sheep on glucose and oxygen metabolism in utero in fed conditions and after maternal fasting for 48 h near term. Fetal adrenalectomy (AX) had little effect on the rates of glucose and oxygen metabol...
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Insulin deficiency affects the adult metabolic response to undernutrition, but its effects on the fetal response to maternal undernutrition remain unknown. This study examined the effects of maternal fasting for 48 h in late gestation on the metabolism of fetal sheep made insulin deficient by pancreatectomy (PX). The endocrine and metabolic responses to maternal fasting differed between intact,...
متن کاملAdrenal Glands Are Essential for Activation of Glucogenesis
31 In adults, the adrenal glands are essential for the metabolic response to stress but little is known 32 about their role in fetal metabolism. This study examined the effects of adrenalectomizing fetal 33 sheep on glucose and oxygen metabolism in utero in fed conditions and after maternal fasting for 34 48h near term. Fetal adrenalectomy (AX) had little effect on the rates of glucose and oxyg...
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OBJECTIVES Evidence that fetal development has long-term impacts on health has increased interest in maternal-fetal nutrient exchange. Although maternal metabolism is known to change during gestation to accommodate fetal nutrient demands, little is known about these modifications outside of a Western, clinical context. This study characterizes maternal metabolic adaptations to pregnancy, and th...
متن کاملMaternal Factors Associated with Fetal Growth and Birthweight Are Independent Determinants of Placental Weight and Exhibit Differential Effects by Fetal Sex
INTRODUCTION Maternal nutritional and metabolic factors influence the developmental environment of the fetus. Virtually any nutritional factor in the maternal blood has to pass the placental membranes to reach the fetal blood. Placental weight is a commonly used measure to summarize placental growth and function. Placental weight is an independent determinant of fetal growth and birthweight and...
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ورودعنوان ژورنال:
- Reproduction, nutrition, developpement
دوره 28 3B شماره
صفحات -
تاریخ انتشار 1988